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Extracellular vesicles shed by multidrug resistant cells contribute to the identification of SRC inhibitors as chemosensitizers in non-small cell lung cancer
Open Access Original Article 10 Feb 2026
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Novel anti-tumor strategies: targeting the crosstalk between cancer stem cells and cancer-associated fibroblasts to resist drug resistance
Open Access Review 20 Jan 2026
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Identification of antibody-drug conjugate payloads that are substrates of ATP-binding cassette drug efflux transporters
Open Access Original Article 12 Jan 2026
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Circular RNA hsa-circ-0001030 suppresses proliferation and cisplatin tolerance in TSCC via interaction with PKM2
Open Access Original Article 7 Jan 2026
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MicroRNAs as key regulators of cancer drug resistance: insights and future directions in chemotherapy, targeted-therapy, radiotherapy, and immunotherapy
Open Access Review 10 Dec 2025
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Unraveling resistance to immune checkpoint inhibitors in HNSCC: from mechanisms to combination therapies
Open Access Review 5 Dec 2025
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Disrupting resistance: novel therapeutic approaches to combat multidrug resistance in fusion-negative rhabdomyosarcoma
Open Access Review 3 Dec 2025
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Osimertinib acquired resistance among patients with EGFR-mutated NSCLC: from molecular mechanisms to clinical therapeutic strategies
Open Access Review 2 Dec 2025
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Overcoming cancer drug resistance through small-molecule targeting of HSP90 and HSP70
Open Access Review 1 Dec 2025
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Mechanisms of resistance to antibody-drug conjugates in cancer therapy: molecular basis and therapeutic strategies
Open Access Review 28 Nov 2025
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RCC1 knockdown sensitizes drug-resistant colorectal cancer to 5-fluorouracil or doxorubicin by impairing DNA repair
Open Access Original Article 10 Nov 2025
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Novel FAK inhibitors suppress tumor growth and reverse EGFR-TKI resistance in non-small cell lung cancer
Open Access Original Article 5 Nov 2025
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Circular RNA-based liquid biopsy: a promising approach for monitoring drug resistance in cancer
Open Access Review 30 Oct 2025
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Targeting tumor-draining lymph node to overcome resistance to cancer immunotherapy: an update
Open Access Review 24 Oct 2025
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Recent progress on tyrosine kinase inhibitors resistance in renal cell carcinoma: another brick in the wall?
Open Access Review 15 Oct 2025
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KLF5 promotes tumor proliferation and oxaliplatin resistance via chromatin remodeling in KRAS-mutated colorectal cancer
Open Access Original Article 10 Oct 2025
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CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway
Open Access Original Article 26 Sep 2025
DOI: 10.20517/cdr.2025.38
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Cisplatin resistance in head and neck squamous cell carcinoma is linked to DNA damage response and cell cycle arrest transcriptomics rather than poor drug uptake
Open Access Original Article 19 Sep 2025
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