Editorial Board

Godefridus J. Peters

gj.peters@amsterdamumc.nl

Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (Amsterdam UMC), Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Department of Biochemistry, Medical University of Gdansk, Gdansk, Poland.

Research Interests:  cancer biomarkers, apoptosis, lung diseases, cell culture, gene expression, pharmacokinetics, pharmacodynamics and pharmacogenetics of anticancer drugs, gastrointestinal cancers, translational research, animal models, drug metabolism and transport, influx and efflux proteins.

Research Interests: cancer biomarkers, apoptosis, lung diseases, cell culture, gene expression, pharmacokinetics, pharmacodynamics and pharmacogenetics of anticancer drugs, gastrointestinal cancers, translational research, animal models, drug metabolism and transport, influx and efflux proteins.

Wafik S. El-Deiry

Legorreta Cancer Center, Brown University, Providence, RI, USA.

Research Interests:  autophagy, p53 tumor suppression, cell death signaling pathways, DNA damage, TRAIL pathway, hypoxia, drug resistance, novel therapeutics, translational oncology.

Research Interests: autophagy, p53 tumor suppression, cell death signaling pathways, DNA damage, TRAIL pathway, hypoxia, drug resistance, novel therapeutics, translational oncology.

Elisa Giovannetti

Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers (Amsterdam UMC), Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Cancer Pharmacology Lab, Fondazione Pisana per la Scienza, Pisa, Italy.

Research Interests:  molecular pharmacology, chemoresistance, pancreatic cancer, thoracic cancers.

Research Interests: molecular pharmacology, chemoresistance, pancreatic cancer, thoracic cancers.

Paola Perego

Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Research Interests:  molecular biology, p53, DNA damage, apoptosis, cytotoxicity, pharmacology, cancer cell line.

Research Interests: molecular biology, p53, DNA damage, apoptosis, cytotoxicity, pharmacology, cancer cell line.

Chiara Riganti

Department of Oncology, University of Torino, Torino, Italy.

Research Interests:  chemo-immunoresistant tumor models, lung cancer, prostate cancer, breast cancer, malignant pleural mesothelioma, glioblastoma multiforme, multiple myeloma.

Research Interests: chemo-immunoresistant tumor models, lung cancer, prostate cancer, breast cancer, malignant pleural mesothelioma, glioblastoma multiforme, multiple myeloma.

Baiyong Shen

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Research Interests:  pancreatic cancer, drug resistance mechanisms, molecular targeting, precision medicine, tumor microenvironment, immune suppression, PDX models, targeted therapy, chemotherapy sensitivity, metabolic reprogramming.

Research Interests: pancreatic cancer, drug resistance mechanisms, molecular targeting, precision medicine, tumor microenvironment, immune suppression, PDX models, targeted therapy, chemotherapy sensitivity, metabolic reprogramming.

Hailin Tang

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

Research Interests:  cancer, metastasis, metabolism, animal model, non-coding RNA.

Research Interests: cancer, metastasis, metabolism, animal model, non-coding RNA.

Suresh V. Ambudkar

Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Research Interests:  ATP-binding cassette (ABC) drug transporters, drug resistance, membrane biochemistry, chemoresistance, transport proteins.

Research Interests: ATP-binding cassette (ABC) drug transporters, drug resistance, membrane biochemistry, chemoresistance, transport proteins.

Yehuda G. Assaraf

Department of Biology, Technion-Israel Institute of Technology, Haifa, Israel.

Research Interests:  molecular mechanisms of anticancer drug resistance, drug discovery, physiology.

Research Interests: molecular mechanisms of anticancer drug resistance, drug discovery, physiology.

Maria R. Baer

University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.

Research Interests:  acute myeloid leukemia, FLT3 internal tandem duplication, signaling pathways, kinase inhibitors, drug resistance.

Research Interests: acute myeloid leukemia, FLT3 internal tandem duplication, signaling pathways, kinase inhibitors, drug resistance.

Stergios Boussios

Faculty of Life Sciences and Medicine, King's College London, London, UK.

Research Interests:  cancer treatment, cancer in pregnancy, cancer diagnostics, cancer biology, cancer biomarkers, gynaecological cancers, urological cancers, colorectal cancer, autoimmunity.

Research Interests: cancer treatment, cancer in pregnancy, cancer diagnostics, cancer biology, cancer biomarkers, gynaecological cancers, urological cancers, colorectal cancer, autoimmunity.

Claudio Cerchione

Hematology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.

Research Interests:  myelodysplastic syndromes, hematological malignancies, lymphoma, multiple myeloma, hematologic diseases, clinical hematology, blood disorders, acute myeloid leukemia, chemotherapy, leukemia, acute lymphoblastic leukemia.

Research Interests: myelodysplastic syndromes, hematological malignancies, lymphoma, multiple myeloma, hematologic diseases, clinical hematology, blood disorders, acute myeloid leukemia, chemotherapy, leukemia, acute lymphoblastic leukemia.

Zhesheng Chen

Department of Pharmaceutical Sciences, St. John’s University, Queens, NY, USA.

Research Interests:  ABC transporters, multidrug resistance, cancer pharmacology.

Research Interests: ABC transporters, multidrug resistance, cancer pharmacology.

Liang Cheng

Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School, Brown University Health, Providence, RI, USA.

Research Interests:  pathology, biomarker, genitourinary malignancies, bladder cancer.

Research Interests: pathology, biomarker, genitourinary malignancies, bladder cancer.

William C Cho

Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, China.

Research Interests:  cancer biomarkers, drug repurposing, non-coding RNA, proteomics.

Research Interests: cancer biomarkers, drug repurposing, non-coding RNA, proteomics.

Mario Cioce

Laboratory of Molecular Medicine and Biotechnology, University Campus Bio-Medico of Rome, Rome, Italy.

Research Interests:  mesothelioma, metformin, CSC, translational oncology, chemoresistance, TKI, Ephrin, EMT.

Research Interests: mesothelioma, metformin, CSC, translational oncology, chemoresistance, TKI, Ephrin, EMT.

Jacqueline Cloos

Department of Hematology, VU University Medical Center, Amsterdam, Netherlands.

Research Interests:  proteasome inhibitors, minimal residual disease, clonal evolution, splicing, cellular drug addiction, hematology, drug combination studies.

Research Interests: proteasome inhibitors, minimal residual disease, clonal evolution, splicing, cellular drug addiction, hematology, drug combination studies.

Paul Dent

Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USA.

Research Interests:  cancer therapeutics, rational combination of drugs, molecular mechanisms, drug combinations synergize, breast, brain, liver and pancreatic cancers.

Research Interests: cancer therapeutics, rational combination of drugs, molecular mechanisms, drug combinations synergize, breast, brain, liver and pancreatic cancers.

Changming Dong

School of Chemistry & Chemical Engineering, Shanghai Jiao Tong University, Shanghai, China.

Research Interests:  biodegradable polymer nanomedicine, cancer combination therapy, drug delivery systems, multidrug resistance.

Research Interests: biodegradable polymer nanomedicine, cancer combination therapy, drug delivery systems, multidrug resistance.

Thomas Efferth

Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.

Research Interests:  natural product chemistry, medicinal and pharmaceutical chemistry, virtual drug screening, transcriptomics, network pharmacology, biochemistry, drug development, apoptosis, cancer biology.

Research Interests: natural product chemistry, medicinal and pharmaceutical chemistry, virtual drug screening, transcriptomics, network pharmacology, biochemistry, drug development, apoptosis, cancer biology.

Marco Falasca

Curtin Health Innovation Research Institute, Curtin University, Perth, Australia.

Research Interests:  pancreatic cancer, exosomes, lipid metabolism, membrane transporters, signal transduction, cancer invasion and metastasis, phosphoinositide signalling, cannabinoids.

Research Interests: pancreatic cancer, exosomes, lipid metabolism, membrane transporters, signal transduction, cancer invasion and metastasis, phosphoinositide signalling, cannabinoids.

Liwu Fu

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

Research Interests:  ABC transporter, cancer therapy, chemotherapy resistance, multidrug resistance, immune checkpoint blockade, leukemia.

Research Interests: ABC transporter, cancer therapy, chemotherapy resistance, multidrug resistance, immune checkpoint blockade, leukemia.

David A. Gewirtz

Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.

Research Interests:  autophagy, senescence, cancer chemotherapy, chemosensitization, radiosensitization, chemtoxicity.

Research Interests: autophagy, senescence, cancer chemotherapy, chemosensitization, radiosensitization, chemtoxicity.

Jean-Pierre Gillet

Laboratory of Molecular Cancer Biology, Faculty of Medicine, University of Namur, Namur, Belgium.

Research Interests:  ATP-binding cassette transporters, cancer multidrug resistance mechanisms, pharmacogenomics, cancer biology, transcriptomics.

Research Interests: ATP-binding cassette transporters, cancer multidrug resistance mechanisms, pharmacogenomics, cancer biology, transcriptomics.

William Gmeiner

Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Research Interests:  colorectal cancer, fluoropyrimidine, thymidylate synthase, DNA topoisomerase, aberrant signaling pathways in tumor cells.

Research Interests: colorectal cancer, fluoropyrimidine, thymidylate synthase, DNA topoisomerase, aberrant signaling pathways in tumor cells.

Michael M Gottesman

Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Research Interests:  cancer therapy, drug resistance, nanotechnology, theranostics, biomarker.

Research Interests: cancer therapy, drug resistance, nanotechnology, theranostics, biomarker.

Alessandro Granito

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Department of Medical and Surgical Sciences (DIMEC),University of Bologna, Italy.

Research Interests:  hepatocellular carcinoma, primary liver cancer, intrahepatic cholangiocarcinoma, cancer immunology, liver immunology, cancer immunotherapy, tyrosine kinase inhibitors, transarterial chemoembolization, radioembolization.

Research Interests: hepatocellular carcinoma, primary liver cancer, intrahepatic cholangiocarcinoma, cancer immunology, liver immunology, cancer immunotherapy, tyrosine kinase inhibitors, transarterial chemoembolization, radioembolization.

Nadia M. Hamdy

Faculty of Pharmacy, Biochemistry and Molecular Biology Department, Ain Shams University, Cairo, Egypt.

Research Interests:  Non-coding RNAs (lncRNA/miRNA/piRNA/circRNAs), epigenetic regulation in cancer, tumor microenvironment, targeted therapy and precision oncology, signaling pathways in cancer, biomarkers for diagnosis and prognosis, translational cancer therapeutics.

Research Interests: Non-coding RNAs (lncRNA/miRNA/piRNA/circRNAs), epigenetic regulation in cancer, tumor microenvironment, targeted therapy and precision oncology, signaling pathways in cancer, biomarkers for diagnosis and prognosis, translational cancer therapeutics.

Dominique Heymann

Institut de Cancérologie de l'Ouest, Tumour Heterogeneity and Precison Medicine Laboratory, Saint-Herblain, France.

Research Interests:  circulating tumour cells, pathogenesis of bone sarcoma, osteoclast differentiation, metastatic process.

Research Interests: circulating tumour cells, pathogenesis of bone sarcoma, osteoclast differentiation, metastatic process.

Zhiqing Huang

Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Duke University Medical Center, Durham, NC, USA.

Research Interests:  ovarian cancer, cancer chemoresistance, tumor microenvironment, epigenetics and epigenomics.

Research Interests: ovarian cancer, cancer chemoresistance, tumor microenvironment, epigenetics and epigenomics.

Thomas E. Hutson

Hematology and Medical Oncology, UC Davis Health, Sacramento, CA, USA;
UMC Cancer Center, Lubbock, TX, USA; Texas Tech University Health Science Center, Lubbock, TX, USA.

Research Interests:  renal cell carcinoma, bladder cancer, prostate cancer, testicular cancer, immunotherapy.

Research Interests: renal cell carcinoma, bladder cancer, prostate cancer, testicular cancer, immunotherapy.

Gerrit Jansen

Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands.

Research Interests:  rheumatology, cancer biology and immunology, imaging and biomarkers, inflammatory diseases, antifolates, proteasome inhibitors, (multi) drug resistance.

Research Interests: rheumatology, cancer biology and immunology, imaging and biomarkers, inflammatory diseases, antifolates, proteasome inhibitors, (multi) drug resistance.

Hang Fai Kwok

Faculty of Health Sciences, University of Macau, Macau, China.

Research Interests:  novel therapeutic antibodies development, venom-based peptide & natural biomolecule prototype drugs development, cancer biomarkers & immunotherapy markers discovery for prognostic and therapeutic validation.

Research Interests: novel therapeutic antibodies development, venom-based peptide & natural biomolecule prototype drugs development, cancer biomarkers & immunotherapy markers discovery for prognostic and therapeutic validation.

Saverio Marchi

Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.

Research Interests:  cell signaling, cancer biology, cell death, molecular cell biology, mitochondria, calcium.

Research Interests: cell signaling, cancer biology, cell death, molecular cell biology, mitochondria, calcium.

Enrico Mini

Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence, Italy.

Research Interests:  leukemia, antimetabolites and metal-based drug resistance, gastrointestinal cancers, cancer pharmacogenomics, pharmacogenetics.

Research Interests: leukemia, antimetabolites and metal-based drug resistance, gastrointestinal cancers, cancer pharmacogenomics, pharmacogenetics.

Gianpaolo Papaccio

Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

Research Interests:  cancer stem cells, peritumoral tissue, mitochondrial transfer, organoids, adipose stem cells and cancer, hyaluronans and cancer.

Research Interests: cancer stem cells, peritumoral tissue, mitochondrial transfer, organoids, adipose stem cells and cancer, hyaluronans and cancer.

Roger M. Phillips

Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.

Research Interests:  tumour hypoxia, cancer metabolism, hypoxia activated prodrugs, drug discovery (including phenotypic drug evaluation), drug delivery to the tumour microenvironment.

Research Interests: tumour hypoxia, cancer metabolism, hypoxia activated prodrugs, drug discovery (including phenotypic drug evaluation), drug delivery to the tumour microenvironment.

Raphael E. Pollock

Department of Surgery, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.

Research Interests:  sarcoma, neoplasms, neurilemmoma, gastrointestinal stromal tumors, breast neoplasms, leiomyosarcoma, neoplasm metastasis, ewing, liposarcoma, myxoid, liposarcoma.

Research Interests: sarcoma, neoplasms, neurilemmoma, gastrointestinal stromal tumors, breast neoplasms, leiomyosarcoma, neoplasm metastasis, ewing, liposarcoma, myxoid, liposarcoma.

Paolo Ettore Porporato

Department of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Turin, Turin, Italy.

Research Interests:  cancer metabolism, muscle atrophy, mitochondrial ROS, cachexia, iron.

Research Interests: cancer metabolism, muscle atrophy, mitochondrial ROS, cachexia, iron.

Changsong Qi

Peking University Cancer Hospital, Beijing, China.

Research Interests:  Cell therapy, clinical trail, solid tumor, immunotherapy, targeted therapy, Gastrointestinal cancer (GI cancer), gastrointestinal stromal tumor (GIST).

Research Interests: Cell therapy, clinical trail, solid tumor, immunotherapy, targeted therapy, Gastrointestinal cancer (GI cancer), gastrointestinal stromal tumor (GIST).

Jiangjiang Qin

Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou, Zhejiang, China.

Research Interests:  gastric cancer, pancreatic cancer, new target discovery, molecular mechanism of new targets, innovative drugs.

Research Interests: gastric cancer, pancreatic cancer, new target discovery, molecular mechanism of new targets, innovative drugs.

Robert W. Robey

Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Research Interests:  cancer drug resistance, ATP-binding cassette transporters, ABCG2, histone deacetylase inhibitors, METTL7A.

Research Interests: cancer drug resistance, ATP-binding cassette transporters, ABCG2, histone deacetylase inhibitors, METTL7A.

Ahmad R Safa

Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN, USA.

Research Interests:  cancer drug resistance, cancer stem cells, apoptosis resistance, anti-apoptotic roteins, pro-apoptotic proteins.

Research Interests: cancer drug resistance, cancer stem cells, apoptosis resistance, anti-apoptotic roteins, pro-apoptotic proteins.

John D. Schuetz

Department of Pharmacy and Pharmaceutical Science, St. Jude Children's Research Hospital, Memphis, TN, USA.

Research Interests:  role of ABC transporters in response to chemotherapy, biological function of ABC transporters, regulation of ABC transporters.

Research Interests: role of ABC transporters in response to chemotherapy, biological function of ABC transporters, regulation of ABC transporters.

Gautam Sethi

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore.

Research Interests:  cancer, cellular and molecular mechanisms, diagnostics and therapeutics, gastrointestinal cancer.

Research Interests: cancer, cellular and molecular mechanisms, diagnostics and therapeutics, gastrointestinal cancer.

John Seymour

Peter MacCallum Cancer Centre, Royal Melbourne Hospital & University of Melbourne, Victoria, Australia.

Research Interests:  haematology, aggressive lymphoma, acute leukemia, myelodysplasia.

Research Interests: haematology, aggressive lymphoma, acute leukemia, myelodysplasia.

Jianliang Shen

Wenzhou Medical University, Zhejiang, China.

Research Interests:  micro/nanomedicine, hybrid biomaterial, drug delivery, cancer immunotherapy, tissue engineering

Research Interests: micro/nanomedicine, hybrid biomaterial, drug delivery, cancer immunotherapy, tissue engineering

Dean G Tang

Professor & Chairman, Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Research Interests:  cancer stem cells, prostate cancer, stem cells, cancer cell heterogeneity, lineage plasticity, therapy resistance, cancer vaccine.

Research Interests: cancer stem cells, prostate cancer, stem cells, cancer cell heterogeneity, lineage plasticity, therapy resistance, cancer vaccine.

Kenneth Kin Wah To

School of Pharmacy, the Chinese University of Hong Kong, Hong Kong, China.

Research Interests:  multidrug resistance in cancer chemotherapy, drug repurposing, cancer epigenetics.

Research Interests: multidrug resistance in cancer chemotherapy, drug repurposing, cancer epigenetics.

Robert C.A.M. van Waardenburg

Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA.

Research Interests:  DNA repair proteins, cellular response to chemotherapy, protein-protein interactions, post-translational modification by ubiquitin and SUMO, sulfotransferases.

Research Interests: DNA repair proteins, cellular response to chemotherapy, protein-protein interactions, post-translational modification by ubiquitin and SUMO, sulfotransferases.

Erik A. C. Wiemer

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.

Research Interests:  cancer biology, biomarkers, non-coding RNAs, soft tissue sarcomas, lung cancer, ovarian cancer.

Research Interests: cancer biology, biomarkers, non-coding RNAs, soft tissue sarcomas, lung cancer, ovarian cancer.

Dong-Hua Yang

New York College of Traditional Chinese Medicine, Mineola, NY, USA.

Research Interests:  biomarker, pharmacology, multi-drug resistance, cancer biology, Chinese medicine, immunohistochemistry.

Research Interests: biomarker, pharmacology, multi-drug resistance, cancer biology, Chinese medicine, immunohistochemistry.

Qing Zhou

Guangdong Lung Cancer Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.

Research Interests:  lung cancer, targeted therapy, immunotherapy, tumor microenvironment, tumor metabolism.

Research Interests: lung cancer, targeted therapy, immunotherapy, tumor microenvironment, tumor metabolism.