fig6

From: Flexible and immunomodulatory milk-derived protein hydrogels as transient interfacing scaffolds for peripheral nerve integration

Figure 6. (A) Immunohistochemical staining of CD86 and CD206 at an early time point (scale bar = 100 μm); Quantification of positive expression of (B) CD86 and (C) CD206 (^*P < 0.05 and ^***P < 0.001 vs. MDP, ^@@P < 0.01 and ^@@@P < 0.001 vs. MDP-DOPA); (D) qRT-PCR evaluation of transcript levels for genes involved in inflammatory responses, macrophage polarization, and tissue repair calibrated against the autograft group (^*P < 0.05, ^**P < 0.01, and ^***P < 0.001 vs. MDP, ^@P < 0.05, ^@@P < 0.01, and ^@@@P < 0.001 vs. MDP-DOPA). Values represent mean ± SD from quadruplicate biological experiments. MDP: Milk-derived protein; DOPA: dihydroxyphenylalanine; qRT-PCR: quantitative reverse transcription polymerase chain reaction; SD: standard deviation; DAPI: 4′,6-diamidino-2-phenylindole.