fig1
Figure 1. HSPs induce drug resistance in cancers via various mechanisms. HSP90, HSP70, sHSPs, and other HSPs contribute to resistance by sequestering therapeutic agents, stabilizing DNA repair proteins to enhance repair capacity, and regulating drug efflux transporters to reduce intracellular drug accumulation. This figure was generated by the PowerPoint software. HSPs: Heat shock proteins; sHSPs: small heat shock proteins.
