Volume 3, Issue 4 (December, 2024) – 12 articles
Cover Picture: The authors evaluate the complexity of discrimination between these two synbiotic concepts using an exemplary study performed with a panel of Lactiplantibacillus plantarum (L. plantarum) strains to identify strain-specific synergistic synbiotics that eventually turned out to work via a complementary synbiotic mechanism. This study highlights that assessing the in situ selectivity of synergistic synbiotics in the intestinal tract is challenging due to the confounding effects of the substrate ingredient on the endogenous microbiome, thereby raising doubts about the added value of distinguishing between synergistic and complementary concepts in synbiotics.
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