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MicroRNAs as key regulators of cancer drug resistance: insights and future directions in chemotherapy, targeted-therapy, radiotherapy, and immunotherapy

Unraveling resistance to immune checkpoint inhibitors in HNSCC: from mechanisms to combination therapies

Targeting tumor-draining lymph node to overcome resistance to cancer immunotherapy: an update

Targeting the hypoxia signaling pathway with nanomedicine to reverse immunotherapy resistance

Effects of FAP⁺ cancer-associated fibroblasts on anti-PD-1 immunotherapy and CD4⁺ T cell polarization in gastric cancer

Integrated multi-omics profiling of immune microenvironment and drug resistance signatures for precision prognosis in prostate cancer

ZEB2 upregulation modulates the polarization of TAMs toward the immunosuppressive state in EGFR-TKI-resistant NSCLC

Tumor microenvironment-driven resistance to immunotherapy in non-small cell lung cancer: strategies for Cold-to-Hot tumor transformation

Sophisticated roles of tumor microenvironment in resistance to immune checkpoint blockade therapy in hepatocellular carcinoma

Overcoming drug resistance in castrate-resistant prostate cancer: current mechanisms and emerging therapeutic approaches

Exploring YAP1-related TIME in SCLC: implications for survival and treatment response to immuno-chemotherapy

Integrative multi-omics analysis for identifying novel therapeutic targets and predicting immunotherapy efficacy in lung adenocarcinoma