fig10

Figure 10. Effect of Muno-IgY® on cytokine production. Cytokine levels were measured in Caco-2/PBMC co-cultures exposed to SHIME® day8 effluents. Statistical significance was assessed by a paired t-test (P < 0.05). Values are expressed as mean ± SD normalized to control (n = 9 replicates). Different letters above bars indicate statistically significant differences between treatments. IFN-γ: Interferon-γ; IL-17A: Interleukin-17A; IL-21: Interleukin-21; IL-22: Interleukin-22; IL-4: Interleukin-4; IL-9: Interleukin-9; IgY: immunoglobulin Y; PBMC: peripheral blood mononuclear cell; SD: standard deviation.