fig6

Figure 6. GSEA of key genes. (A-E) KEGG pathway enrichment analysis of key genes, including associated signaling pathways and contributing genes. GSEA: Gene set enrichment analysis; C2: complement component 2; GUCY1B2: guanylate cyclase 1 soluble subunit beta 2; OLFM4: olfactomedin 4; ITPR1: inositol 1,4,5-trisphosphate receptor type 1; KLHL36: kelch like family member 36; KEGG: kyoto encyclopedia of genes and genomes; mTOR: mechanistic target of rapamycin; MAPK: mitogen-activated protein kinase; TNF: tumor necrosis factor; TGF: transforming growth factor; IL-17: interleukin-17.