fig4

Estimating drinking water PFAS exposures associated with serum clinical action levels using a probabilistic toxicokinetic model

Figure 4. Model-predicted serum concentrations for 6-month-old, exclusively breastfed infants for a suite of PFAS at varying maternal drinking water exposure levels. The stated drinking water concentration determines maternal serum PFAS concentrations and breast milk concentrations. Vertical black lines are the modeled distribution of serum PFAS concentrations at each drinking water exposure level, with the median shown as a point and the horizontal bars showing the 5th and 95th percentiles. The blue regression line depicts the linear relationship at the 90th percentile of predicted serum values. The red horizontal line shows the NASEM 20 ng/mL clinical action level. PFAS: Per- and polyfluoroalkyl substances; NASEM: National Academies of Sciences, Engineering, and Medicine; PFOA: perfluorooctanoic acid; PFOS: perfluorooctanesulfonic acid; PFHxS: perfluorohexanesulfonic acid; PFNA: perfluorononanoic acid; PFDA: perfluorodecanoic acid; PFHpA: perfluoroheptanoic acid.

Journal of Environmental Exposure Assessment
ISSN 2771-5949 (Online)

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