fig7

PM<sub>2.5</sub> and O<sub>3</sub> co-exposure affecting serum LDL-C: evidence from epidemiology and animal models

Figure 7. mRNA and protein expression levels of LDL-C uptake-related genes in rat liver. (A) represents the mRNA expression levels of the target genes, with the vertical axis showing the relative mRNA expression of the target genes normalized to the internal reference gene β-actin; (B and C) show the immunohistochemical staining results and statistical comparison for the target proteins LDLR and PCSK9, respectively; *P < 0.05. LDLR: Low-density lipoprotein receptor; LDL-C: low-density lipoprotein cholesterol; PCSK9: proprotein convertase subtilisin/kexin type 9.

Journal of Environmental Exposure Assessment
ISSN 2771-5949 (Online)

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