fig8

Bioinspired mechanosensitive ion channels: design principles and emerging applications

Figure 8. Schematic diagram of the application of bioinspired mechanosensitive ion channels, including promoting apoptosis, artificial skin, and nanofluidic iontronic memristor. (A) Mechanically sensitive butterfly-shaped K+ channels encourage apoptosis in cells by disrupting potassium ion homeostasis. Reproduced with permission[19]. Copyright 2025, Wiley-VCH; (B) Illustration of human skin and Ionic mechanoreceptor skin before and under stimulation. Reproduced with permission[115]. Copyright 2019, Springer Nature; (C) Highly asymmetric channels as the I-V characteristics and schematic diagram of nanofluid memristors. Reproduced with permission[121]. Copyright 2024, Springer Nature. G4C7: Mechanically and pH dual-gated butterfly-shaped artificial ion channel; DMSO: dimethyl sulfoxide; PDMS: poly(dimethylsiloxane); ROFF: conductance ratio in the off state; Ron: conductance ratio in the on state rout: radius of outside; rin: radius of inside; rblister: radius of blister.