fig5

Bioinspired mechanosensitive ion channels: design principles and emerging applications

Figure 5. Schematic diagram of the bioinspired ion channel based on flexible polymer nanochannels. (A) The PI-b-P4VP-based bioinspired mechanosensitive ion channel. Upon mechanical stimulation of the membrane, the P4VP channel undergoes significant deformation. Reproduced with permission[18]. Copyright 2023, American Chemical Society; (B) Illustration of modifying the inner wall of the channel for fine-tuning the pore size. Reproduced with permission[104]. Copyright 2024, Elsevier; (C) The bioinspired photo-responsive polymer ion channels. Reproduced with permission[99]. Copyright 2024, Springer Nature. Light induces the formation of porphyrins inside, generating surface charges that promote the formation of chloride ion channels. PI-b-P4VP: Polyisoprene-b-poly4-vinylpyridine.