fig4
From: Hepatocellular carcinoma tumor immune microenvironment: heterogeneity and therapeutic strategies
Figure 4. Multidimensional regulatory strategies for HCC immunotherapy and tumor. Created in BioRender. ICI: Immune-checkpoint inhibitor; CTLA-4: cytotoxic T-lymphocyte-associated protein 4; PD-1: programmed cell death protein 1; PD-L1: programmed cell death ligand 1; TIL: tumor-infiltrating lymphocyte; CAR-T: chimeric antigen receptor T cell; TCR-T: T-cell receptor-engineered T cell; TME: tumor microenvironment; ACT: adoptive cell therapy; SCFA: short-chain fatty acid; CAFs: cancer-associated fibroblasts.
