fig5

Figure 5. Computational prediction of LGR6 association with the WNT pathway and TP53 in prostate cancer. (A) Functional enrichment analysis of LGR6 co-expressed genes in the WNT signaling pathway. (B) Correlation analysis between LGR6 expression and the pan-cancer stemness index (RNAss) across various cancer types. (C) Correlation analysis between LGR6 expression and WNT signal pathway-related gene sets (Pearson’s correlation test). (D) Regulatory network of LGR6 and key oncogenes (e.g., TP53). (E) Predicted three-dimensional structure and interaction model between LGR6 and TP53 proteins.