REFERENCES
1. Watson, J. D.; Crick, F. H. C. Molecular structure of nucleic acids: a structure for deoxyribose nucleic acid. Nature 171, 737-8 (1953).
2. Wang, F. Element as a mirror - revealing science’s essence and distant horizons. Element 1, 1 (2025).
3. Ferry, G. James D. Watson. Lancet 406, 2416 (2025). https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02330-X/fulltext. (accessed 2025-12-25).
4. Ledford, H.; Lenharo, M.; Maher, B.; Watson, T. DNA pioneer James Watson has died - colleagues wrestle with his legacy. Nature 647, 563-4 (2025).
5. Ewalt, D. M. James Watson, who helped discover the structure of DNA, is dead at age 97. Scientific American (New York, NY, USA). November 7, 2025. https://www.scientificamerican.com/article/james-watson-co-discoverer-of-dna-dead-at-97/. (accessed 2025-12-25).
6. Wade, J.; Byrne, D. J.; Ballentine, C. J.; Drakesmith, H. Temporal variation of planetary iron as a driver of evolution. Proc. Natl. Acad. Sci. U. S. A. 118, e2109865118 (2021).
7. Martin, W.; Russell, M. J. On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells. Philos. Trans. R. Soc. Lond. B Biol. Sci. 358, 59-85 (2003).
8. Dixon, S. J. et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149, 1060-72 (2012).
9. Galy, B.; Conrad, M.; Muckenthaler, M. Mechanisms controlling cellular and systemic iron homeostasis. Nat. Rev. Mol. Cell Biol. 25 ,133-55 (2024).
10. Ru, Q.; Li, Y.; Chen, L.; Wu, Y.; Min, J.; Wang, F. Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects. Signal Transduct. Target. Ther. 9, 271 (2024).
11. Wang, X. et al. Adipocyte-derived ferroptotic signaling mitigates obesity. Cell Metab. 37, 673-91.e7 (2025).
13. Tsvetkov, P. et al. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science 375, 1254-61 (2022).
14. Chen, L.; Min, J.; Wang, F. Copper homeostasis and cuproptosis in health and disease. Signal Transduct. Target. Ther. 7, 378 (2022).
16. Sun, S. et al. The intestinal transporter SLC30A1 plays a critical role in regulating systemic zinc homeostasis. Adv. Sci. 11, e2406421 (2024).
17. Pavletich, N. P.; Pabo, C. O. Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 Å. Science 252, 809-17 (1991).
18. Roy, A.; Cisneros, G. A. Comparison of magnesium and manganese ions on the structural and catalytic properties of human DNA polymerase gamma. J. Chem. Theory Comput. 21, 9094-106 (2025).
