fig3

Figure 3. The relationship between circRNAs and signaling pathways. The shapes at the top represent oncogenic elements, while those at the bottom indicate tumor-suppressive elements. Pink and blue circles represent circRNAs, while orange shapes denote proteins. Linear shapes indicate miRNAs, and blue squares represent major pathways. X indicates pathway inhibition. A triple arrowhead signifies pathway activation. An arrow with a T-shaped tip represents downregulation, whereas a normal arrow represents upregulation.