fig1

Figure 1. Categories and biogenesis of circRNAs. (A) Intron pairing-driven circularization and RBP-driven circularization; (B) After back-splicing, EcircRNAs or ElciRNAs are generated; (C) Alternative back-splicing. EcircRNAs: Exonic circRNA; EIciRNAs: exonic intronic circRNAs; RBP: RNA-binding protein; 1: exon 1; 2: exon 2.